Name: Yongjie Wu
Professional Title：Professor
E-mail: wuyj@lzu.edu.cn
Research Interests: Antitumor Pharmacology; Preclinical Pharmacology of New Drugs and Anti-inflammatory Pharmacology
Education/Training:
1984 Shanxi Medical College M.S. in Pharmacology
1999 Lanzhou Medical College Student in Clinical Medicine
Awards&Honors:
1. 1992 obtained the honor of The Young Teachers Chengcai Award in Gansu Province;
2. 1998 obtained the honor of Academic technology leaders of Gansu Province;
3. 2006 obtaine the second prize of Gansu Provincial Science and Technology Progress Award (First author) for Sdudy on Enteral delivery systems of Proanthocyanidin from Grape Seeds;
4. 2006 obtained the second prize of Gansu Provincial Natural Science (Third author) for the Mechanisms of Proanthocyanidin from Grape Seeds in both Potentiating Anti-tumor Activity and Reducing Toxicity of Doxorubicin;
5. 2006 obtained the honor of special allowance of Government of the State Council。
Projects:
National Natural Science Foundation of China, 30672490, 2007.01-2009.12
Publications:
1. Cui MX, Yang LN, Wang XX, Wang L, Li RL, Han W, Wu YJ*. Alleviative effect of ciliary neurotrophic factor analogue on high fat-induced hepatic steatosis is partially independent of the central regulation. Clin Exp Pharmacol Physiol. 2017; 44:395–402.
2. Cui MX, Jiang JJ, Min GN, Han W, and Wu YJ*. Ciliary Neurotrophic Factor Analogue Aggravates CCl4-induced Acute Hepatic Injury in Rats. Canadian Journal of Physiology and Pharmacology. 2017;95:620–623.
3. Wan Li, Qi-Long Wang, Xia Liu, Shu-Hong Dong, Hong-Xia Li, Chun-Yang Li,Li-Shu Guo, Jing-Miao Gao, Nathan A. Berger, Li Li, Lan Ma, and Yong-Jie Wu*. Synergistic Chemopreventive Effects on Colorectal Neoplasia in Rats and Mice. Cancer. Prev. Res, 2015，8(2)：139-148
4. Baolai Zhang1,*, Shuhong Dong1, Zhongxin Li, Li Lu, Su Zhang, Xue Chen, Xiaobo Cen, and Yongjie Wu*. Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta？catenin. Journal of Translational Medicine, 2015, 13:394.
5. Li-Shu Guo, Hong-Xia Li, Chun-Yang Li, Sheng-Yan Zhang, Jia Chen, Qi-Long Wang, Jing-Miao Gao, Jia-Qi Liang,Ming-Tang Gao, Yong-Jie Wu* Synergistic antitumor activity of vitamin D3 combined with metformin in human breast carcinoma MDA-MB-231 cells involves m-TOR related signaling pathways. Pharmazie 2015,70: 117–122
6. Li-Shu Guo, Hong-Xia Li, Chun-Yang Li, Sheng-Yan Zhang, Jia Chen, Qi-Long Wang, Jing-Miao Gao, Jia-Qi Liang,Ming-Tang Gao, Yong-Jie Wu* Vitamin D3 enhances antitumor activity of metformin in human bladder carcinoma SW-780 cells. Pharmazie 2015.70: 123–128
7. Hong-Xia Li, Jing-Miao Gao, Jia-Qi Liang, Jun-Min Xi, Meng Fu and Yong-Jie Wu* Vitamin D3 potentiates the growth inhibitory effects of metformin in DU145 human prostate cancer cells mediated by AMPK/mTOR signalling pathway. Clinical and Experimental Pharmacology and Physiology 2015,42:711–717
8. National invention patent ZL200810208119.2, 2013.02.18
9. National invention patent ZL200810033775.3, 2012.05.16
10.National invention patent ZL200610025335.4, 2011.01.12
