Name: Li Min
Professional Title：Full Professor，
Chief Physician
Office: 511, Jingcheng Building, Lanzhou University
E-mail: limin@lzu.edu.cn
Research Interests:
Researches concerned with neoplastic invasion and metastasis
Empirical studies involved in antineoplastic functions of traditional Chinese herbs
Education/Training:
1978.09-1983.06 Major in clinical medicine. Graduated from Lanzhou Medical College and acquied the Bachelor's Degree.
1988.09-1991.06 Lucubrating Masters’ Degree in Pathology in Lanzhou Medical College
2001.09-2007.06 Lucubrating Doctors’ Degree in Biochemistry and Molecular Biology in Lanzhou University.
2018.01-2018.02 Senior visiting fellow, Molecular Oncology Program epartment of Surgery Sylvester Comprehensive Cancer Center University of Miami Miller School of Medicine.
Awards&Honors:
Trans-century academic leaders in colleges and universities, Gansu Province.
The '333' talent first and second-level candidates, Gansu Province.
A member of of Expert Group, Medical Identification Committee, Health Department, Gansu Province.
Representative of The 12th session of the People's Congress of Lanzhou City.
Lecturer of of Excellent Courses-Pathology, Gansu Province.
Series researches in pathogenic mechanism and therapic strategies of gastric carcinoma, the first prize of Gansu Province Scientific and Technological Progress in 2010.
Experimental study of NO, ET in the regulation status of circulatory function and the relationship with septic shock, the third prize of Gansu Province Scientific and Technological Progress in 2002.
Expression and clinical significance of vascular endothelial growth factor, cyclooxygenase -2 and CD44V6 in Borderline ovarian tumor, the second prize of Gansu Province Scientific and Technological Progress in 2005.
Immunohistochemical study of breast tumor estrogen receptor and laminin, the third prize of Gansu Health Department Scientific and Technological Progress in 1997.
Projects:
Microparticles-bound VWF mediates microparticle-induced transendothelial migration of gastric cancer cells:A novel mechanism of cancer metastasis. National Natural Science Foundation of China research grants.2017.1－2020.12
The role and mechanism of von Willebrand Factor in the hematogenous sprean of gastrointestinal malignant tumor. National Natural Science Foundation of China research grants.2014.1－2014.12
Demonstration of prevention and control mode in high incidence area of malignant tumor in Wuwei city. Ministry of science and technology projects for the benefit of the people.2013.1－2015.12
Development and quality evaluation system of new bone,cartilage and composite tissue engineering products was established.Major science and technology projects in Gansu province. 2013.1－2015.12
Ultrafiltration technology to extract effective components of angelica sinensis and astragalus radiation-resistant and new products for cancer treatment. Major science and technology projects in Gansu province.2009.9－2012.9
The anticancer active substance of Qinglongyi was screened by metabolomics method based on HPLC. National Natural Science Foundation of China research grants.2008.1-2010.12
The study of correlation of clotting factor FⅧ,vWF and thrombotic disease.Gansu province science and technology support program.2013.1－2015.12
A preliminary study on the effects of heavy ions and X-rays on autophagy and autophagy of colon cancer stem cells in radiotherapy.Heavyion beam radiation biomedical key laboratory opentopic.2011.1－2012.12
Effects of autophagy on the survival of colon cancer cells in hypoxic microenvironment. Gansu province natural science research fund plan. 2011.1－2013.12
Study on antitumor activity and action mechanism of acanthopanax senticosus extract from Gansu province.Project of Gansu provincial administration traditional Chinese medicine. 2008.1－2009.
Publications:
Cancer Cell-derived von Willebrand Factor Enhanced Metastasis of Gastric Adenocarcinoma. Oncogenesis,2018, 7(1):12
COPB2 suppresses cell proliferation and induces cell cycle arrest in human colon cancer via regulation cell cycle related proteins.Experimental and Therapeutic Medicine. 2018. 777-784
Lactadherin Promotes Microvesicle Clearance to Prevent Coagulopathy and Improves Survival of Severe TBI Mice. Blood ,2018,131(5),563-572
Cellular microparticles and pathophysiology of traumatic brain injury. Protein&Cell,2017
Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury-associated coagulopathy in mice .Blood ,2016, 127(2),2763-2772
Enhanced autophagy reveals vulnerability of P-gp mediated
epirubicin resistance in triple negative breast cancer cells. Apoptosis .2016.21(4):473–488
Brain-Derived Microparticles Induce Systemic Coagulation Associated With Traumatic Brain Injury. Blood ,2015, 125(13):2151-2159
NME2 Reduces Proliferation, Migration and Invasion of Gastric Cancer Cells to Limit Metastasis. PloS one ,2015;10(2):e0115968
AICAR inhibited proliferation, induced S-phase arrest and promoted apoptosis in CaSki cells Acta Pharmacol Sin 2007，28:1984-1990
Correlation of COX-2 and K-ras expression to clinical outcome in gastric cancer ACTA Oncological 2006，45:1115-1119
