Name: Baolai Zhang

Professional Title：Associate Professor

Office:

E-mail: zhangbl@lzu.edu.cn

Research Interests: Pharmacology of New Drugs Epigenetics in cancer,

 

Education/Training: 

2014  Sichuan University  Ph.D. in Pharmacology

2005  Lanzhou University  M.S. in Medicine

1999  Lanzhou Medical College  B.S. in Medicine

 

Awards&Honors:

2017 Excellent guidance teacher in undergraduate innovation and entrepreneurship action plan of Lanzhou University

 

Projects: 

Fundamental Research Funds of the Central Universities The Role and Mechanism of the Protein Arginine Methyltransferase 5 in human hepatocellular carcinoma 2013.01-2014.06 and Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models 2009.01-2011.09

 

Publications:

1. Baolai Zhang^1*, Xue Chen¹, Suying Ge, Caili Peng, Su Zhang, Xu Chen, Tao Liu, and Wenkai Zhang. Arginine methyltransferase inhibitor 1 inhibits mouse sarcoma growth in vitro and in vivo. Oncology letters, 2018, 16, 2161-2166.

2.   Shuhong Dong¹, Xing Wang¹, Sanchun Tian, Nengqian Ma, Xinyang Zhang, Yapeng Liu, Baolai Zhang^* and Yongjie Wu^*. Arginine methyltransferase inhibitor 1 exhibits antitumor effects against cervical cancer in vitro and in vivo. Pharmazie, 2018, 73: 269–273.

3.   Baolai Zhang^1,*, Su Zhang¹, Lijuan Zhu, Xue Chen, Yunfeng Zhao, Li Chao, Juanping Zhou, Xing Wang, Xinyang Zhang, Nengqian Ma. Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5. Toxicology and Applied Pharmacology, 2017, 336:1-7.

4.   Baolai Zhang, Shuhong Dong, Ruiming Zhu, Chunyan Hu, Jing Hou, Yan Li, Qian Zhao, Xue Shao, Qian Bu, Hongyu Li, Yongjie Wu, Xiaobo Cen^* and Yinglan Zhao^*. Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3. Oncotarget, 2015, 6 (26):22799-22811.

5.   Baolai Zhang^1,*, Shuhong Dong¹, Zhongxin Li, Li Lu, Su Zhang, Xue Chen, Xiaobo Cen, and Yongjie Wu^*. Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta？catenin. Journal of Translational Medicine, 2015, 13:394.

6.  Baolai Zhang, Shuhong Dong, Xiaobo Cen, Xiao Wang, Xia Liu, Hongxia Zhang, Xin Zhao, Yongjie Wu^*. Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models. Anticancer Drugs, 2012, 23 (6):590-96.

7.   Baolai Zhang, Bei Gao, Shuhong Dong, Yingqi Zhang, Yongjie Wu^*. Anti-tumor efficacy and pre-clinical immunogenicity of IFNa2a-NGR，Regul Toxicol Pharmacol, 2011, 60(1):73–78.