Name: Jingjing Song
Professional Title:Assistant Professor
Office:
Research Interests: Drug development of peptide-drug conjugates.
Education/Training: 2014 Lanzhou University Ph.D. in Biochemistry
and molecular biology
Awards&Honors: 2017 The 2017 School of Basic Medical Sciences Teaching Competition for Young Teachers First Award
2018 The 2017 Lanzhou University Teaching Competition for Young Teachers Second Award
2018 The Fifth Lanzhou University School of Medicine Teaching Competition for Young Teachers Second Award
Projects:
1. NNSFC Design and application evaluation of novel peptide gene vector in therapeutic genome editing 2017/01-2019/12
Publications: (限10项)
1. Kai M,Zhang W,Xie H,Liu LW, Huang SJ,Li X, Zhang ZZ, Liu YY, Zhang BZ, Song JJ *,Wang R*. Effects of linker amino acids on the potency and selectivity of dimeric antimicrobial peptides. Chinese Chemical Letters. 2018, 29:1163-9.
2. Song JJ, Zhang Y, Zhang W, Chen J, Yang X, Ma P, Zhang B, Liu B, Ni J*, Wang R*. Cell penetrating peptide TAT can kill cancer cells via membrane disruption after attachment of camptothecin. Peptides. 2015,63:143-9.
3. Chen G, Song JJ, Zhang H, Jiang Y, Liu W, Zhang W*, Wang B*. Pd nanoparticles encapsulated in magnetic carbon nanocages: an efficient nanoenzyme for the selective detection and multicolor imaging of cancer cells. Nanoscale. 2015,7:14393-400.
4. Zhang Y, Song JJ, Zhang W, Liang R, Ma Y, Zhang L, Wei X, Ni J*, Wang R*. Functional properties of a novel hybrid antimicrobial peptide NS: potent antitumor activity and efficient plasmid delivery. J Pept Sci. 2014,20(10):785-93.
5. Zhang W 1, Song JJ 1, Liang RR, Zheng X, Chen JB, Li GL, Zhang BZ, Yan X, Wang R*. Stearylated antimicrobial peptide melittin and its retro isomer for efficient gene transfection. Bioconjugate Chem, 2013, 24:1805-1812.
6. Zhang W1, Song JJ 1, Liang RR, Zheng X, Chen JB, Li GL, Zhang BZ, Wang KR, Yan X, Wang R*. Stearylated antimicrobial peptide [D]-K6L9 with cell penetrating property for efficient gene transfer. Peptides, 2013, 46C:33-39.
7. Song JJ 1, Zhang W 1, Kai M, Chen J, Liang R, Zheng X, Li G, Zhang B, Wang K, Zhang Y, Yang Z, Ni J, Wang R. Design of an Acid-Activated Antimicrobial Peptide for Tumor Therapy. Mol Pharm. 2013,10: 2934-2941.
8. Song JJ, Kai M, Zhang W, Zhang JD, Liu LW, Zhang BZ, Liu X, Wang R*. Cellular uptake of transportan 10 and its analogs in live cells: Selectivity and structure–activity relationship studies. Peptides, 2011, 32:1934-1941.
9. Zhang W1, Song JJ1, Zhang BZ, Liu LW, Wang KR, Wang R*. Design of acid-activated cell penetrating peptide for delivery of active molecules into cancer cells. Bioconjugate Chem, 2011, 22:1410-1415.
10. Zhang W1, Song JJ1, Mu LY, Zhang BZ, Liu LW, Xing YH, Wang KR, Li ZY, Wang R*. Improving anticancer activity and selectivity of camptothecin through conjugation with releasable substance P. Bioorg Med Chem Lett, 2011, 21:1452-1455.