Name: Hongxia Niu
Professional Title£ºAssistant Professor£¬
Master¡¯s Supervisor
Office: Lanzhou University
E-mail: niuhx@lzu.edu.cn
Research Interests: Bacteria persistence infection and host immune response
Education/Training:
2012.09¨C2015.06 Ph.D. in Genetics, Lanzhou University
2014.01¨C2015.01 Exchange PhD student, Johns Hopkins University
2009.09¨C2012.07 M.S. in Pathogen Biology, Lanzhou University
2004.09¨C2009.07 B.S. in Medicine, Xinxiang Medical University
Awards & Honors:
2017 Second Award of Lecture contest of young teachers, School of Basic Medical Sciences, Lanzhou University
2015 Outstanding Graduates Awards, Lanzhou University
Projects:
1. The national natural science foundation of China (NNSFC) (81701969), The mechanism of chaperone SurA increasing persistence in E. coli. 2018.01-2020.12 , Project Leader
2. The Fundamental Research Funds for the Central Universities[lzujbky-2018-85], The regulation of surA in E. coli£¬2018.01-2019.12, Project Leader
3. The national natural science foundation of China (NNSFC) (31470895), The characteristics of memory T cell subtype induced by TB subunit vaccine, 2015.01-2018.12£¬ Project Member
4. The National Natural Science Foundation of China (31470895), The development of innovative Tuberculosis (TB) vaccines, 2012.01-2015.12, Project Member
5. The national Natural Science Foundation of China (81701969), The development of Tuberculosis (TB) vaccines, 2008.10 -2010.12, Project Member
Publications:
1. Hongxia Niu#, Rebecca Yee, Peng Cui, Lili Tian, Shuo Zhang, Wanliang Shi, David Sullivan, Wenhong Zhang, Bingdong Zhu, Ying Zhang *, Identification of Agents Active against Methicillin-Resistant Staphylococcus aureus USA300 from a Clinical Compound Library. Pathogen6(3),44 (2017).
2. Hongxia Niu#, Chao ma, peng cui, Waniang Shi, Shuo Zhang, Jie feng, David Sullivan, Bingdong Zhu, Whenhong Zhang and Ying Zhang*, Identification of drug candidates that enhance pyrazinamide activity from a clinical compound library. Emerging Microbles & Infections 6, e27(2017).
3. Hongxia Niu#, Peng Cui, Rebecca Yee, Wanliang Shi, Shuo Zhang, Jie Feng, David Sullivan, Wenhong Zhang, Bingdong Zhu, Ying Zhang *, A Clinical Drug Library Screen Identifies Tosufloxacin as Being Highly Active against Staphylococcus aureus Persisters, Antibiotics, 2015, 4:329-336
4. Hongxia Niu#, Jinxiu Peng, Chunxiang Bai, Xun Liu, Lina Hu, Yanping Luo, Bingxiang Wang, Ying Zhang, Jianzhu Chen, Hongjuan Yu, Qiaoyang Xian, Bingdong Zhu *, Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice, PLos One, 2015,10(6)
5. Hongxia Niu#, Peng Cui#, Wanliang Shi, Shuo Zhang, Jie Feng, Yong Wang, David Sullivan, Wenhong Zhang, Bingdong Zhu, Ying Zhang*, Identification of Anti-Persister Activity against Uropathogenic Escherichia coli from a Clinical Drug Library, Antibiotics, 2015, 4:179-187
6. Qi Xin#, Hongxia Niu#, Zhi Li#, Guoping Zhang, Lina Hu, Bingxiang Wang, Jingjing Li, Hongjuan Yu, Wanbo Liu, Yue Wang, Zejiao Da, Ruiyin Li, Qiaoyang Xian, Yong Wang, Ying Zhang, Tao Jing, Xingming Ma, Bingdong Zhu *, Subunit Vaccine Consisting of Multi-Stage Antigens Has High Protective Efficacy against Mycobacterium tuberculosis Infection in Mice, PLos One, 2013, 8(8)
7. Hongxia Niu#, Lina Hu, Qing Li, Zejiao Da, Bingxiang Wang, Kefeng Tang, Qi Xin, Hongjuan Yu, Ying Zhang, Yong Wang, Xingming Ma, Bingdong Zhu *, Construction and evaluation of amultistage Mycobacterium tuberculosis subunit vaccine candidate Mtb10.4-HspX, Vaccine, 2011, 29:9451-9458
8. Bingdong Zhu, Hongxia Niu, Jinxiu Peng, Chunxiang Bai, Lina Hu, Xun Liu, Bingxiang Wang, Yanping Luo, Hongjuan Yu, Hong Wang, Hongfei Kang, Fei Li. The Construction, Expression, Purification of M. tuberculosis Fusion Protein EAMMH and its Application for Vaccine. 2017.06.16 China, ZL201410187154.6. Issued Patent
9. Bingdong Zhu, Hongxia Niu, Lina Hu, Qing Li, Bingxiang Wang, Zejiao Da, Yan Wan, Weimin Ma. The Construction, Expression, Purification of M. tuberculosis Fusion Protein Mtb10.4-Hsp16.3 and its Application for Vaccine. 2012.11.28, China, ZL201010613320. Issued Patent
